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Apoptosis Ruxolitinib Detoxification Epidemiology Silica Granulocyte-macrophage colony-stimulating factor Pulmonary arterial hypertension Cancer Hepatocytes Whole lung lavage Cardiovascular Diesel exhaust particles Lait France Comorbidity Human hepatocytes Aryl hydrocarbon receptor Diesel exhaust Diagnosis Drug transporter Regulation Eleveurs de bétail Chronic obstructive pulmonary disease Bretagne Dendritic cells Cigarette smoke Hepatoma Cytochrome P450 COPD Drug interactions Dairy farmers Fibrose pulmonaire Heterocyclic amines Air pollution Crystalline silica Immunotoxicity Pneumopathie infiltrante diffuse Environmental risk factors Cytochrome P-450 Dust exposure Toxicokinetics Pharmacokinetics Inhibition Polycyclic aromatic hydrocarbon Oxidative stress Hepatocyte Bacteria Polarization Genotoxicity Bisphenol A Nrf2 Gene expression Inflammation Macrophage Hospital Chest tube drainage Systemic sclerosis Drug–drug interactions Bronchopneumopathie chronique obstructive Inorganic arsenic Camp Cell signaling Polycyclic aromatic hydrocarbons Idiopathic pulmonary fibrosis Drug-drug interactions Carcinogens Pirfenidone Interstitial lung disease Calcium Drug transporters Docking HepaRG cells Cardiovascular diseases Exposition professionnelle Differentiation Acid sphingomyelinase Benzoapyrene Lung Scleroderma Toxicity Cytokine Pesticides Treatments NF-κB Arsenic Stress Macrophages GM-CSF Bactérie Chest tube Cancer du pancréas Risque professionnel Efferocytosis Hypertension artérielle pulmonaire Toxicité AhR Cytokines Humans Nintedanib Farmer