Granulocytic sarcoma of the choroid plexus complicating acute leukemia

Caroline Apra (1, 2) , Pierre Bourdillon (1, 2, 3)

1 ICM - Institut du Cerveau et de la Moëlle Epinière = Brain and Spine Institute
2 HCL - Hospices Civils de Lyon
3 UCBL - Université Claude Bernard Lyon 1

A 38-year-old patient with type 5 acute myeloid leukemia relapsed after 4 years of treatment including chemotherapy and bone marrow transplant. He underwent imaging for vertigo, with an otherwise normal neurologic examination. Brain MRI showed diffuse choroid plexus enlargement, without hydrocephalus, a rare typical image of granulocytic sarcoma (figure, A).1 The patient also had spine MRI, to explore right L5 radiculopathy, which showed signs of meningitis with radicular and diffuse epidural enhancement (figure, B).

Mots clés: brain MRI; acute leukemia; choroid plexus hypertrophy; hematology; granulocytic sarcoma

Domaines: Cancer; Neurobiologie

Caroline Apra, Pierre Bourdillon. Granulocytic sarcoma of the choroid plexus complicating acute leukemia . Neurology, 2017, 89 (19), pp.2019-2020. ⟨10.1212/WNL.0000000000004632⟩. ⟨hal-01643538⟩