Assessment of clinically relevant bleeding as a surrogate outcome for major bleeding: validation by meta-analysis of randomized controlled trials

S. Laporte (1) , C. Chapelle (1) , L. Bertoletti , E. Ollier (2) , P. Zufferey (1) , C. Lega , A. Merah , H. Decousus (1) , S. Schulman (3) , G. Meyer (4) , Michel Cucherat (5) , P. Mismetti (1)

1 GRT (EA 3065) - Groupe de recherche sur la thrombose
2 CEA-LETI - Commissariat à l'énergie atomique et aux énergies alternatives - Laboratoire d'Electronique et de Technologie de l'Information
3 Center for Hematology
4 LaPEC - EA4278 Laboratoire de Pharm-Ecologie Cardiovasculaire
5 Evaluation et modélisation des effets thérapeutiques

Domains: Life Sciences [q-bio]; Human health and pathology

S. Laporte, C. Chapelle, L. Bertoletti, E. Ollier, P. Zufferey, et al.. Assessment of clinically relevant bleeding as a surrogate outcome for major bleeding: validation by meta-analysis of randomized controlled trials. Journal of Thrombosis and Haemostasis, 2017, 15 (8), pp.1547-1558. ⟨10.1111/jth.13740⟩. ⟨hal-02112953⟩